I0634
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I0634
Sigma
Ionomycin calcium salt from Streptomyces conglobatus
powder, ≥98% (HPLC)
| CAS Number: | 56092-82-1 |
| Linear Formula: | C41H70CaO9 |
| Molecular Weight: | 747.07 |
| Beilstein Registry Number: | 1416163 |
| MDL number: | MFCD00151183 |
Description
| Preparation Note | Store ionomycin in powder form desiccated and protected from light at 2-8 °C. Under these conditions the product is stable for 3 years. Store stock solutions in ethanol or DMSO at -20 °C, protected from light. Under these conditions the stock solutions are stable for several months. For short term use (up to 6 weeks) the stock solutions maybe stored at 2-8 °C protected from light. |
| Biochem/physiol Actions | Ca2+ ionophore that is more effective than A23187 as a mobile ion carrier for Ca2+; non-fluorescent; used to study Ca2+ transport across biological membranes; induces apoptotic degeneration of embryonic cortical neurons. |
Properties
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| protect from light | |
| color | white to off-white |
| solubility | DMSO: ~1 mg/mL |
| ethanol: soluble | |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| WGK Germany | 3 |
| RTECS | NO0650000 |
References
| reference | Toeplitz, B.K., et al. J. Am. Chem. Soc. 101, 3344, (1979) |
